Lithium dodecyl sulfate (LDS) is an anionic detergent that is widely used in electrophoresis, proteomics studies and chromatography. It is also used to solubilize membrane proteins in non-denaturing conditions. It has been used as a substitute for sodium dodecyl sulfate in electrophoresis. The product is available in standard packaging or custom-packed. You can also use its conversion calculator.
LDS has been extensively studied in micellar electrokinetic chromatography and has been shown to partition between water and bilayer membranes. In addition, it has been shown to act as a reverse filter. These liquid membranes can be used to separate particles in solution, which has resulted in the development of SDS-based liquid membranes that can serve as a particle separator. For this reason, LDS is often substituted for sodium dodecyl sulfate.
Dodecyl sulfate is soluble in high concentrations of cesium chloride and is considered to be a highly effective detergent, despite the fact that it has a relatively low boiling point. Furthermore, dodecyl sulfate has been known to stabilize RNA for hours to days, which is important when animal cells are unlocked. Besides its detergent properties, dodecyl sulfate can release nucleic acids from protein structures. Therefore, it has been used in combination with phenol in a variety of applications.
There is a wide range of uses for lithium dodecyl sulfate, including synthesis of nanomaterials. However, this product is only for laboratory research purposes and is not intended for commercial usage. Because of its anionic nature, dodecyl sulfate requires careful handling and is a hazardous substance.